Mining copper transport genes
نویسندگان
چکیده
منابع مشابه
Mining copper transport genes.
C is not only a ubiquitous metal in our modern, technological environment, it is also essential for the function of most living organisms. Just as it allows for the movement of electrons through wires, it helps catalyze the movement of electrons within biological molecules. Making up only 0.01% of the Earth’s crust, it is relatively scarce in the environment and must be actively scavenged. Unti...
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Copper is an essential micronutrient that is toxic in excess. To maintain an adequate yet non-toxic concentration of copper, cells possess several modes of control. One involves copper uptake mediated by genes encoding proteins that play key roles in high affinity copper transport. These include the FRE1-encoded Cu2+/Fe3+ reductase and the CTR1 and CTR3-encoded membrane-associated copper transp...
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Primary aldosteronism is the most common form of secondary hypertension and is present in about 8% to 10% of patients with hypertension. In primary aldosteronism, aldosterone secretion is excessive and relatively autonomous of the normal regulatory mechanisms.1,2 It was originally described by Jerome Conn from the University of Michigan3 and is thought to be due to an aldosterone-producing aden...
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The successful pathogen targets host defenses at multiple points; indeed, the number of targets and the breadth of strategies for disarming these defenses are quite amazing. To target host defenses, the pathogen secretes effector proteins, which act to suppress defenses and to manipulate host metabolism to favor pathogen growth and transmission (reviewed in Hogenhout et al., 2009). To protect t...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2001
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.131192498